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KNOWN HAZARDS: Although we have found no reports of toxicity for this species, a number of ferns contain carcinogens so some caution is advisable. Many ferns also contain thiaminase, an enzyme that robs the body of its vitamin B complex. In small quantities this enzyme will do no harm to people eating an adequate diet that is rich in vitamin B, though large quantities can cause severe health problems. The enzyme is destroyed by heat or thorough drying, so cooking the plant will remove the thiaminase. (Plants for a Future)
In the British Isles, wall rue was considered a specific remedy for scrofula many years ago. This is a form of tuberculosis characterized by festering abscesses and swelling of the glands in the neck. (Ferns of Grey and Bruce Counties)
This plant is in the the endangered species list of COSEWIC (Committee on the Status of Endangered Wildlife in Canada)
True to its name, wall rue almost always grows on vertical rocky surfaces. (Connecticut Botanical Society)
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