Observation: Onychogryphosis is an acquired nail plate change. It often affects the toenail. It is a thickening of the nail plate, with associated gross hyperkeratosis and increased curvature. Cutaneous Leishmaniasis (CL) is a major world health problem that is growing epidemically in many areas of the world including our region (Syria).We described unusual case of Onychogryphosis caused by Paronychial Form of Cutaneous Leishmaniasis in the right index finger which has not been previously reported. Key Words: Cutaneous Leishmaniasis, Paronychial Form, Onychogryphosis