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α-Ketoglutaric acid sodium salt (CAS 22202-68-2)

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Alternate Names:
2-oxoglutarate monobasic
CAS Number:
22202-68-2
Purity:
≥98%
Molecular Weight:
168.08
Molecular Formula:
C5H5NaO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Monosodium oxoglurate (MSG) is a versatile amino acid derivative utilized in various applications, spanning from food flavorings and preservatives to laboratory experiments. It presents itself as a white crystalline powder with an odorless nature and a slightly salty taste. Widely employed in the food industry as a flavor enhancer and preservative, MSG has also found application in scientific research endeavors. It has been instrumental in studies delving into cell physiology, metabolism, and gene expression.

References:

  1. Development of amperometric alpha -ketoglutarate biosensor based on ruthenium-rhodium modified carbon fiber enzyme microelectrode.  |  Poorahong, S., et al. 2011. Biosens Bioelectron. 26: 3670-3. PMID: 21334188
  2. Multienzyme-modified biosensing surface for the electrochemical analysis of aspartate transaminase and alanine transaminase in human plasma.  |  Han, YD., et al. 2011. Anal Bioanal Chem. 400: 797-805. PMID: 21359826
  3. Nine post-translational modifications during the biosynthesis of cinnamycin.  |  Ökesli, A., et al. 2011. J Am Chem Soc. 133: 13753-60. PMID: 21770392
  4. Electrophysiological characterization of human and mouse sodium-dependent citrate transporters (NaCT/SLC13A5) reveal species differences with respect to substrate sensitivity and cation dependence.  |  Zwart, R., et al. 2015. J Pharmacol Exp Ther. 355: 247-54. PMID: 26324167
  5. A Micro-Platinum Wire Biosensor for Fast and Selective Detection of Alanine Aminotransferase.  |  Thuy, TN. and Tseng, TT. 2016. Sensors (Basel). 16: PMID: 27240366
  6. Identification of Ligand-Receptor Interactions: Ligand Molecular Arrays, SPR and NMR Methodologies.  |  Day, CJ., et al. 2017. Methods Mol Biol. 1512: 51-63. PMID: 27885598
  7. Mathermycin, a Lantibiotic from the Marine Actinomycete Marinactinospora thermotolerans SCSIO 00652.  |  Chen, E., et al. 2017. Appl Environ Microbiol. 83: PMID: 28576760
  8. Metabolites-Enabled Survival of Crucian Carps Infected by Edwardsiella tarda in High Water Temperature.  |  Jiang, M., et al. 2019. Front Immunol. 10: 1991. PMID: 31507599
  9. A family of radical halogenases for the engineering of amino-acid-based products.  |  Neugebauer, ME., et al. 2019. Nat Chem Biol. 15: 1009-1016. PMID: 31548692
  10. Highly Sensitive Amperometric alpha -Ketoglutarate Biosensor Based on Reduced Graphene Oxide-Gold Nanocomposites.  |  Peng, G., et al. 2020. Int J Anal Chem. 2020: 4901761. PMID: 32802061
  11. Detection of D-glutamate production from the dual Function enzyme, 4-amino-4-deoxychorismate Lyase/D-amino Acid Transaminase, in Mycobacterium smegmatis.  |  Opel-Reading, HK., et al. 2019. Bio Protoc. 9: e3135. PMID: 33654763
  12. Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.  |  Chen, D., et al. 2021. Mol Cell. 81: 3833-3847.e11. PMID: 34289383
  13. Algorithm-aided engineering of aliphatic halogenase WelO5* for the asymmetric late-stage functionalization of soraphens.  |  Büchler, J., et al. 2022. Nat Commun. 13: 371. PMID: 35042883
  14. Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ.  |  Auman, D., et al. 2022. J Am Chem Soc. 144: 15622-15632. PMID: 35980821

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Ketoglutaric acid sodium salt, 1 g

sc-214449
1 g
$38.00

α-Ketoglutaric acid sodium salt, 5 g

sc-214449A
5 g
$76.00