2. KOILONYCHIA
Reverse curvature in longitudinal &
Transverse axes giving a concave dorsal
aspects of nail
Signs most prominent in great toe & thumb
Iron def anemia in adults
Common feature in infancy great toe
nail,persistence indicative of deficiency of
cysteine rich keratin in Trichothiodystrophy
3. KOILONYCHIA
-Spoon shaped deformity
-Normal Convexity replaced by
Central Concavity
-Surrounded by Distal &
Lateral Margins
-Lichenplanus,hypothyroidism,
hemochromatosis,20- nail
dystrophy
5. BEAUS LINES
Single horizontal ridge by horizontal lines of
darkened cells and linear depressions
It is the result of any interruption in the
protein formation of the nail plate
trauma, illness, malnutrition or any major
metabolic condition, chemotherapy
9. TRACHYONYCHIA (20-NAIL DYSTROPHY,SANDPAPERED NAILS)
Rough surface affecting
all nail plates,idiopathic
forms k/s 20 nail
dystrophy
k/a Sand Blasted Nails
in French means
grey,roughened surface
Alopecia areata,
Psoriasis,Lichen planus
Histology shows
spongiosis &
lymphocytic infiltrate
10. ONYCHOMADESIS(NAIL SHEDDING)
Detachment of the nail
plate from proximal
nail fold,d/t severe
insult that produces
arrest of nail matrix
activity
Proximal detachment
of nail
Most often traumatic
11. ONYCHAUXIS
GREAT TOE NAILS GROSSLY THICKENED WITH
TRANSVERSE RIDGING ( ONYCHAUXIS )
Nail thickening d/t
subungual scales
Subungual hyperkeratosis
psoriasis,onychomycosis,e
czema
12. ONYCHIA
• Inflammation of the nail
matrix
• It is accompanied by pus
formation
• There is Inflammation
within the nail plate
13. ONYCHOCRYPTOSIS (INGROWN TOE NAIL)
Lateral ingrowing usually affects hallux,
great toe
Teenagers,Young adults,congenital
malalignment of big toes nails often
present
Ppt by improper nail cutting and
hyperhidrosis
Growth of granulation tissue undergoes
epithelialization
DD: Multiple Periungual Pyogenic
granulomas d/t retinoids,ART drugs
14. ONYCHOCRYPTOSIS :TREATMENT
Prevention through patient education
Removal of embeded spicule
Uplifting of lateral nail plate
Chemical – 80% Phenol,Laser or Surgical
removal of Lateral Matrix in severe cases
Granulation tissue prevented by topical
antibiotics & steroids,
15. ONYCHOCRYPTOSIS
(INGROWN NAILS)
Also known as ingrown nails
May affect either the fingers or toes
The nail grows into the sides of the flesh &
may cause infection
17. HABIT TIC DEFORMITY
Dystrophic nails
Transverse ridging
Absent of cuticle
Excoriation of Proximal
nail fold
18. ONYCHORRHEXIS
Brittle nails,split vertically, peel or have
vertical ridges.
The result of heredity, the use of strong
solvents in the workplace or the home,
including household cleaning solutions.
Lichen Planus,tumours which compromise
vascular supply
19. ONYCHORRHEXIS
Thinning of Nail plate
Longitudinal ridging &
fissuring
Mild Longitudinal
ridging is characteristic
of Ageing
20. ONYCHOGRYPOSIS
Claw-type nails that are
characterized by a thickened
nail plate
Often the result of trauma
This type of nail plate will
curve inward, pinching the
nail bed and sometimes
require surgical intervention
to relieve the pain.
21. ONYCHATROPHIA
It is an atrophy or
wasting away of the nail
plate
which causes it to lose
its luster, become
smaller & sometimes
shed entirely
Injury or disease may
account for this
irregularity
22. PINCER NAILS
Painful abnormality of nails
Toe >> finger nails
a/w subungual exostosis
Distal nail plate over curved & compresses
subungual tissue
23. BRITTLE NAILS
a vertical splitting or
separation of the nail
plate layers at the distal
(free) edge of the nail
plate
characteristic of the
natural aging process.
overexposure to water
and chemical solvents
such as household
cleaning solutions
25. PACHYONYCHIA CONGENITA
AD,very rare
Hypertrophy of nails occurs a/w nail bed
hyperkeratosis
PC 1: Normal by birth,Progressively
discoloured,thicken more on hands,Palmo-
plantar hyperkeratosis & warty lesions at
knee,elbows,buttocks,Defect Keratins 6a
& 16
PC 2: Less severe nail thickening &
Keratosis, a/w hamartomas,Kinky scalp
hair,epidermal cysts,Defect keratins 6b &
17
28. ANONYCHIA
ABSENCE OF ALL OR PART OF ONE OR SEVERAL NAILS
Congenital:
Mutation in R- Spondin 4
gene
Transient :
Due to nail shedding
Acquired:
Due to scarring of nail
matrix
Trauma,Burns,Surgery,
Lichenplanus.
Epidermolysis bullosa-
irreversible nail loss
29. ANONYCHIA
It is a/w DOOR syndrome,AEC
syndrome,EEC syndrome,TOOD syndrome
Anonychia atrophica : it is an acquired nail
dystrophy,Permanent,secondary to nail
matrix damage
31. MICRONYCHIA
Nails Smaller
Uni or Bilateral
Identifies in Iso- Kikuchi
syndrome,Zimmerman-Laband
syndrome,Turners syndrome
32. MACRONYCHIA
Naila are larger
Uni Or Bilateral
It is a/w Macrodactyly as in
Vonrecklinnghausens disease,Maffucci
syndrome,Klippel-Trenaunay-Weber
syndrome
33. POLYNYCHIA
Existence of two or more separate nails on
one digit
Rare Congenital anomaly
Lawrence-Moon-Biedl syndrome
35. RACKET NAILS
AD
Girls > Boys
Thumbs >> Other fingers
Epiphyses of terminal phalanx of thumb
closes prematurely by age of 7-
10yrs,normally at 13-14 yrs
Distal phalanx of affected thumb is shorter
& wider than normal
Affected nails are opaque,short with loss
of normal curvature
Acquired: cong syphilis,acro osteolysis
37. NAIL PATELLA SYNDROME
AD
Nails partially or totally absent
Linkage b/w locus controlling disorder &
ABO blood group
LMX1B gene plays imp role,located on
long arm of ch 9
Tetrad constitutes Nail
dystrophy,Hypoplastic or absent
patellae,Elbow dysplasia,Iliac horns
Thumb >> other finger
Affected nails 1/3 or 1/2 of normal size
38. NAIL PATELLA SYNDROME
Lunula are triangular or V shaped
Bilateral Post Iliac horns on x-ray
Pathognomonic
Prenatal diagnosis by USG Possible
Other features Lester iris,Open angle
glaucome,Palmoplantar hyperhidrosis,
Scapular hypoplasia
40. ISO KIKUCHI SYNDROME
Nails of index finger small or absent
Unilateral or bilateral
Miconychia is MC presentation
Terminal bifurcation of distal phalanx is
characteristic feature
41. DOLICHONYCHIA
Nails appear narrow & long
Normally ratio b/w length & breadth of nail is
1 + 0.1
In these condition about 1.9
Identified in Ehlers danlos syndrome,Marfans
syndrome
42. CIRCUMFERENTIAL NAILS
Nails are Tubular
Congenital seen in siblings
Nails may cover all sides of one or more
fingers
43. CONGENITAL MALALIGNMENT OF BIGTOE
Lateral deviation of long axis of nail growth
relative to distal phalanx one big toe or
both
Medial deviation is rare
Nails discoloured & thickened,often
traingular in shape
MC identified in Monozygotic & Dizygotic
twins
Nail grows temporarily fast than bone of
hallux,Realignment occurs when bone
growth catches up with nail post natally
44. PERIODIC SHEDDING
Nails of great toe MC affected
AD
One or more nails shed repeatedly
Regrowth of nail incomplete,defective
Trauma from ill fitting shoes is MC cause of
repeated shedding of nails in sports persons
46. CLUBBING
Increased Transverse & Longitudinal nail
curvature with hypertrophy of soft tissue
components of digital pulp
Hyperplasia of fibrovascular tissue at base of
nail gives Rocked nail appearance
Lovibonds angle, Curths angle, Schamroth’s
window
Also K/A Hippocratic nails ,Watch glass nails
49. CLUBBING
Increased blood flow through vasodilated plexus of
nail unit vasculature > Vessel hyperplasia
Altered Vagal tone
Microvascular infarcts
PDGF may responsible for vascular changes
Painful clubbing indicative of periostitis associated
with HPOA,characteristic of thoracic malignancy
Pachydermoperiostosis : idiopathic,Puberty,a/w
spade like thickening of foot & hands
50. CLUBBING
SHELL NAILS RACKET NAILS
Similar to clubbed nails
Girls with bronchiectasis
around 5 yrs age
Avulsion of nail plate
reveals atrophy of nail bed
instead of hypertrophy
noted in true clubbing
Broad & Shortened nails
usually seen thumb & great
toes
Similar to clubbed nails D/T
stubby appearance
Arrest in distal phalangeal
formation
51. CLUBBING
Lovibond angle : angle
at junction of nail plate
& proximal nail fold
Normally less than 160
degrees
Clubbing angle is more
than 180 degrees
52. CLUBBING
Curth’s angle : Angle at
Distal interphalangeal
joint
Normally 180 degrees
Clubbing diminished
less than 160 degrees
61. LICHEN PLANUS
Nail involvement seen in 10 % of patients
with LP
Nail thinning,ridging & fissuring
Cicatricial out come ( Dorsal Pterygium )
Yellowish discolouration
Onycholysis
62. LICHEN PLANUS
Middle Finger :
Proximal nail fold and
matrix caused
trachonychia,Longitudin
al ridging,pterygium
Index Finger :
Destruction of Nail
Plate & Matrix with
anonychia
63. LICHEN PLANUS
Involvement of nail
matrix with pterygium
Scarring
Pt had Hepatitis C virus
with erosive lichen
planus
66. LICHEN PLANUS
HYPERKERATOSIS & SUPERFICIAL
LYMPHOCYTIC INFILTRATE
BAND LIKE SUPERFICIAL LYMPHOCYTIC INFILTRATE
ALONG WITH VACUOLAR DEGENRATION
67. DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)
Nail involvement in 96% cases
Red or white longitudinal streaks ending in a V
shaped notch
Streaks indicative of nail thinning
Subungual hyper keratotic papules in
hyponychium
Histologically similar to acantholysis of skin in
addition of multinucleated giant cells,epithelial
hyperplasia seen
A case of SCC developing in chronic case of
darier disease also noted
68. DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)
Longitudunal streaks (
red & white )
Distal subungual
hyperkeratotic papules
Wedge shaped fissuring
of nail plate
70. RED LUNULA
Erythema of all or part of the lunula may
affect all digits, but most prominently the
thumb
Dotted red lunulae have been reported in
psoriasis and alopecia areata
red lunula seen in a single digit-Local
disturbance of vascular flow- Benign
tumour
Glomus tumour & Subungual myxoid cysts
MC tumours.colour vary from blue & red
71. YELLOW NAIL SYNDROME
The nails are yellow due to
thickening,rarely green tinge possibly due
to secondary infection
There is increased transverse &
longitudinal curvature,loss of cuticle &
Lunula obscured
AD
A/w lymphoedema at one or more sites
and respiratory or nasal sinus disease
72. YELLOW NAIL SYNDROME
Histologically dense fibrous tissue
replacing Subungual stroma with
numerous ectatic epithelium lined
vessels,FB reaction may be seen
Obstruction of lymphatics by dense stroma
leads to the abnormal lymphatic function
found in the affected digits
Recurrent pleural effusions,Ch bronchitis,
bronchiectasis,increased incidence of
malignant neoplasms,nephrotic syndrome
73. YELLOW NAIL SYNDROME
Nails grow at slower rate 0.1-0.25
mm/week ( normal rate 0.5mm/week )
74. YELLOW NAIL SYNDROME
Diffuse Yellow to Green
of nails
Nail thickening
Excessive curvature of
from side to side
75. YELLOW NAIL SYNDROME
Treatment :
- Oral & Topical Vit E
- Oral & Topical Zn
- Pulse Itraconazole 400mg daily /week/month
- Treatment of Chronic infection
- Complete reversion of nail changes may
occur spontaneously
76. HUTCHINSON’S SIGN
Brown black periungual pigmentation
Possible sign of nail melanoma
First described by Hutchinson ,Pigmentation
of proximal nail fold in a/w longitudinal
melanonychia
Also identified in melanocytic naevi
78. GREEN NAIL SYNDROME
Greenish black discolouration d/t Pyocyanin
by P. aeruginosa
Exposure to water,detergents & soaps
Barbers,Bakers & Dish washers
DD: Melanoma,Aspergillus,Melanocytic
naevus
Rx:Aminoglycosides,Acetic acid for 1 to 4
months
79. MEE'S LINES
Transverse white lines that run across the
nail, following the shape of the nail moon
Uncommon
after acute/severe illness, Arsenic poisoning
84. HALF-&-HALF NAILS
K/a Lindsay's nails
Look for an arc of brownish discoloration
May occur in a small percentage of people
who have ch renal failure
Other causes systemic diseases & nutritional
deficiencies
86. SPLINTER HAEMORRHAGES
Looks like a splinter underneath the nail
virtually 100% diagnostic of Sub-acute
Bacterial Endocarditis (SBE)
A bacterial infection affecting the valves of
the heart. Occasionally caused by
Trichinosis, a parasitic infection caused by
eating raw or undercooked Pork.
88. MELANONYCHIA
vertical pigmented bands or nail 'moles‘
a sudden change in the nail plate could
indicate a malignant melanoma or lesion.
Commonly occur in dark-skinned people, and
are normal
Seek physicians care ,If you suddenly see
this change in the nail plate.
90. LEUKONYCHIA
WHITE DISCOLOURATION OF NAILS
True Leukonychia:
Inherited disorder,all nail
affected,milky porcelian white
nails
Subtotal Leukonychia :
Proximal 2/3rd white rest pink d/t
delay in keratin maturation
Transverse Leukonychia:
k/a Mees lines reflect systemic
disorder,chemotheraphy,poisini
ng
Punctate Leukonychia:
White spots of 1-3 mm
size,Manicure,alopecia areata
Apparent Leukonychia:
Changes in nail bed responsible
for white appearance
Terry’s Nails: white
proximally,normal distally,seen
in old age,chronic renal
failure,afterchemotheraphy,cirr
hosis,cardiac failure,histology
shows Inc vessel wall
thickness & Melanin deposition
Muehrcke’s paired white bands
: bands parallel to lunula in nail
bed with pink in b/w white
lines,seen in
hypoalbuminaemia
92. TERRY'S NAILS
The nail looks opaque
and white, but the nail
tip has a dark pink to
brown band.
May accompany
cirrhosis, congestive
heart failure, adult-
onset diabetes, cancer
or ageing.
93.
94. ECZEMA OF THE NAIL
It affect the eponychium, nail plate and bed
It causing pitting and onycholysis.
This is very rare
96. HANG NAILS
Caused by minor injury or constant irritation through biting.
The cuticle splits and appears as a small spike.
Hot oil manicures and regular use of a cuticle oil will help.
The spike can be clipped so it does not catch on things.
97. EGGSHELL NAIL
Nail plate is thin and
abnormally flexible
chronic illness of
systematic or nervous
origin
It curves at the free
edge and the nail plate
can separate from the
nail bed
98. ONYCHOLYSIS
DISTAL OR LATERAL SEPARATION OF NAIL FROM NAIL BED
Psoriatic onycholysis considered as a reference
point for other forms
PO-typically distal,variable lateral involvement,area
of separation appear white or yellow due to air
beneath the nail,sequestered debris & glycoprotien
exudate
Isolated islands of onycholysis present as Oil spots
, salmon patches
99. ONYCHOLYSIS
Idiopathic
-Painless separation of nail from
its bed
-Overzealous manicure,
wetting,cosmetic solvents
-Condition starts at tip of
nail,spreads to distal one third
of nail bed
-Colonization of candida albicans
& pseudomonas pyocyanea
-Affected nails grow very
quickly,more in women,
Secondary
- Psoriasis,trauma,fungal
infections,dermatitis,hypo
thyroidism,yellow nail
syndrome,shell nail
syndrome
- Photoonycholysis :
treatment
withpsoralens,doxycyclin
e,demethylchlortetracycli
ne,retinoids,anti cancer
drugs
103. ONYCHOLYSIS
Treatment :
- Patient advised cut away loosened nail & apply
local steroid with antibiotics ( prevent keratinisation
of nail bed,that slows reattachment of nail)
- Gentamicin eye drops for pseudomonas infection
- 2% thymol in chloroform for preventing infection
- Milton regimen : soaking finger tips several nights
week in venegar or sodium hypochlorite solution for
5 mins for prevention of recurrence
104. ONYCHOMYCOSIS
A fungal or yeast infection which results in
Onychomycosis, can invade through a tear in the
proximal and lateral nail folds as well as the
eponychium.
This type of infection is characterized by
onycholysis with evident debris under the nail plate.
It normally appears white or yellowish in color, and
may also change the texture and shape of the nail.
The fungus digests the keratin protein of which the
nail plate is comprised. As the infection progresses,
organic debris accumulates under the nail plate
often discoloring it.If left untreated, the nail plate
may separate from the nail bed and crumble off.
105. ONYCHOMYCOSIS
(TINEA UNGUIUM)
White spots that can be scraped off the surface, or long yellowish
streaks within the nail substance.
It attacks the free edge & moves towards the matrix
110. ONYCHOMYCOSIS
NAIL CLIPPINGS SHOW SEPTATE
HYPHAL ELEMENTS PROVEN TO BE
TRICHOPHYTON SP WITH IN NAIL
PLATE KERATIN
90 % Toe nail infections with
Trichophyton,Microsporum,Ep
idermophyton sp
PAS staining most sensitive
test
Stain reveals fungal
organisms located in lower
stratum corneum
Distal subungual
Onychomycosis is MC
form,caused by T.rubrum
It invades hyponychium &
LNF finally
yellow,onycholysis,sub ungual
hyperkeratosis
T.mentagrophytes identified in
superficial white OM,located
111. ONYCHOPHAGY
Bitten nails, often no free edge is visible
Nails look ragged and distorted
skin and nail bed can be exposed and raw
112. ONYCOPHOSIS
Refers to the growth of the horny epithelium
in the nail bed
In other words a callus like growth on the
nail plate
113. ONYCHOGRYPHOSIS
Elderly,Commonly toenails,usually Hallux
Favored by trauma
Impairement of peripheral circulation and
innervation
Nail acquires typical Ram’s Horn shape d/t
asymmetric growth
Thick,hard,yellow brown nails
114. ONYCHOPTOSIS
Periodic shedding of one or more nails,
either in whole or parts
This condition may follow certain diseases
such as syphilis
115. PARONYCHIA
Paronychia is associated with separation of
the seal between the proximal nail fold and
the nail plate that provides entry for bacteria
and leads to a localized infection of the
paronychial tissues of the hands.
Symptoms may include inflammation,
swelling & scaling
116. PARONYCHIA
An infectious and
inflammatory condition
of nail folds. Infection is
bacterial
Ch paronychia may
weaken defences and
increase the risk of
developing a fungal
infection of the nail
117. PARONYCHIA
The nail fold is
erythematous,
edematous, with
early abscess
formation, and is
very painful.
119. PTERYGIUM
Pterygium is the inward advance of skin over
the nail plate,
Usually as a result of trauma to the matrix due
to a surgical procedure or by a deep cut to the
nail plate
Pterygium results in the loss of the nail plate due
to the development of scar tissue
Cortisone is used to prevent the advancement of
scar tissue. Never attempt to remove pterygium
-instead, consult a physician for advice and
treatment
NOTE: The 'true cuticle' is often referred to as
Pterygium
120. PTERYGIUM
Pterygium Inversum Unguis is an acquired
forward growth of the hyponychium
characterized by live tissue firmly attached
to the underside of the nail plate, which
contains a blood supply and nerves.
Possible causes are systemic, hereditary,
or from an allergic reaction to acrylics or
solvents.
Never use force to 'push back' the
advancing hyponychium -- it is an
extremely painful approach, and will result
in a blood flow.
121. PTERIGIUM
An abnormal winged like
growth of skin (living
tissue) on the nail plate
The skin is slowly
stretched and dragged
along the bed
caused by severe trauma
such as warts, burns &
blood circulation
disorders.
123. SCABIES OF NAIL
Commonly identified in crusted scabies
Heaped up masses of keratin accummulate
underneath the nail
Subungual material contains abundant
mites,source of infection
Nails become dystrophic
125. SCABIES OF NAIL
Sarcoptes scabiei
present in distal
subungual
hyperkeratotic debris
found in hyponychium
Cause of persistent
epidemics of scabies
Norwegian scabies
severe involvement of
nail folds
Scrapings of distal hyponychium-
showing organism – Sarcoptes Scabiei
126. CANDIDA
Candida parapsilosis account for 20%
infections
Candida common cause of Chronic
paronychia,involve nail bed & nail plate in
HIV
Candida albicans major cause of hypertropic
nail bed infection in paediatric patients with
HIV
129. PSEUDOMONAS
Pseudomonas bacterial infection can occur
between the natural nail plate and the nail bed
Many people have been led to believe that the
classic 'green' discoloration of this type of
infection is some type of mold
In actuality, mold is not a human
pathogen. The discoloration is simply a by-
product of the infection and is caused primarily
by iron compounds
130. PSEUDOMONAS
Pseudomonas thrive in moist places; it
feeds off the dead tissue and bacteria in
the nail plate, while the moisture levels
allow it to grow
The after effects of this infection will
cause the nail plate to darken and soften
underneath an artificial coating
131. PSEUDOMONAS
The darker the discoloration, the deeper into
the nail plate layers the bacteria has
traveled. If the bacteria has entered between
the nail plate and the nail bed, it will cause
the same discolorations and may also cause
the nail plate to lift from the nail bed.
133. ALOPECIA AREATA
First sign in 18% cases,More in children
Pitting of nails,When pits uniformily
distributed on multiple nails,they often
arranged in lines horizontially or vertically in
a geometrical design k/a Glen-Plaid or
Scotch-Plaid Pattern
138. MEDICAL HISTORY
Need to conduct a review of systems (ROS)
Dermatological Conditions important
eg psoriasis, atopy,
Multi-System Disorders
eg RA, SLE, DE, CREST
Cardiac/Pulmonary Problems
Medications review
Surgical Review
Genetics review
140. SUBJECTIVE NAIL ASSESSMENT
Events of Note
How long has problem been present?
Is it getting better or worse?
Is it of concern to the client?
Is pain present?
If so need to evaluate pain
What previous treatments have been attempted?
Professional
OTC
Folk
Need to follow up if any of these answers is positive
141. OBJECTIVE ASSESSMENT OF NAILS
Number of nails affected?
Hands involved?
Colour changes
Extent of colour changes
Extent of general changes
Presence of toe deformity
Presence of local exostosis
May need to examine other areas
Scalp, elbows, knees
142. SPECIAL INVESTIGATIONS
Nail Specific
Biopsy
Microscopy (KOH test)
Culture
X-Ray
Blood Tests
Further Vascular/Neurological Testing
Cardiac Evaluation
Genetic Testing