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ALTERATIONS IN THE NAIL PLATE
DR. YUGANDAR
KOILONYCHIA
 Reverse curvature in longitudinal &
Transverse axes giving a concave dorsal
aspects of nail
 Signs most prominent in great toe & thumb
 Iron def anemia in adults
 Common feature in infancy great toe
nail,persistence indicative of deficiency of
cysteine rich keratin in Trichothiodystrophy
KOILONYCHIA
-Spoon shaped deformity
-Normal Convexity replaced by
Central Concavity
-Surrounded by Distal &
Lateral Margins
-Lichenplanus,hypothyroidism,
hemochromatosis,20- nail
dystrophy
KOILONYCHIA
(SPOON NAIL)
BEAUS LINES
 Single horizontal ridge by horizontal lines of
darkened cells and linear depressions
 It is the result of any interruption in the
protein formation of the nail plate
 trauma, illness, malnutrition or any major
metabolic condition, chemotherapy
BEAU’S LINES
 Multiple transverse
ridging
 Chemotheraphy with
Breast Cancer
Beau’s line;
Zinc deficiency
BEAU’S LINES
TRACHYONYCHIA (20-NAIL DYSTROPHY,SANDPAPERED NAILS)
 Rough surface affecting
all nail plates,idiopathic
forms k/s 20 nail
dystrophy
 k/a Sand Blasted Nails
in French means
grey,roughened surface
 Alopecia areata,
Psoriasis,Lichen planus
 Histology shows
spongiosis &
lymphocytic infiltrate
ONYCHOMADESIS(NAIL SHEDDING)
 Detachment of the nail
plate from proximal
nail fold,d/t severe
insult that produces
arrest of nail matrix
activity
 Proximal detachment
of nail
 Most often traumatic
ONYCHAUXIS
GREAT TOE NAILS GROSSLY THICKENED WITH
TRANSVERSE RIDGING ( ONYCHAUXIS )
 Nail thickening d/t
subungual scales
 Subungual hyperkeratosis
 psoriasis,onychomycosis,e
czema
ONYCHIA
• Inflammation of the nail
matrix
• It is accompanied by pus
formation
• There is Inflammation
within the nail plate
ONYCHOCRYPTOSIS (INGROWN TOE NAIL)
 Lateral ingrowing usually affects hallux,
great toe
 Teenagers,Young adults,congenital
malalignment of big toes nails often
present
 Ppt by improper nail cutting and
hyperhidrosis
 Growth of granulation tissue undergoes
epithelialization
 DD: Multiple Periungual Pyogenic
granulomas d/t retinoids,ART drugs
ONYCHOCRYPTOSIS :TREATMENT
 Prevention through patient education
 Removal of embeded spicule
 Uplifting of lateral nail plate
 Chemical – 80% Phenol,Laser or Surgical
removal of Lateral Matrix in severe cases
 Granulation tissue prevented by topical
antibiotics & steroids,
ONYCHOCRYPTOSIS
(INGROWN NAILS)
 Also known as ingrown nails
 May affect either the fingers or toes
The nail grows into the sides of the flesh &
may cause infection
WASHBOARD NAILS
HABIT TIC DEFORMITY
 Dystrophic nails
 Transverse ridging
 Absent of cuticle
 Excoriation of Proximal
nail fold
ONYCHORRHEXIS
 Brittle nails,split vertically, peel or have
vertical ridges.
 The result of heredity, the use of strong
solvents in the workplace or the home,
including household cleaning solutions.
 Lichen Planus,tumours which compromise
vascular supply
ONYCHORRHEXIS
 Thinning of Nail plate
 Longitudinal ridging &
fissuring
 Mild Longitudinal
ridging is characteristic
of Ageing
ONYCHOGRYPOSIS
 Claw-type nails that are
characterized by a thickened
nail plate
 Often the result of trauma
 This type of nail plate will
curve inward, pinching the
nail bed and sometimes
require surgical intervention
to relieve the pain.
ONYCHATROPHIA
 It is an atrophy or
wasting away of the nail
plate
 which causes it to lose
its luster, become
smaller & sometimes
shed entirely
 Injury or disease may
account for this
irregularity
PINCER NAILS
 Painful abnormality of nails
 Toe >> finger nails
 a/w subungual exostosis
 Distal nail plate over curved & compresses
subungual tissue
BRITTLE NAILS
 a vertical splitting or
separation of the nail
plate layers at the distal
(free) edge of the nail
plate
 characteristic of the
natural aging process.
 overexposure to water
and chemical solvents
such as household
cleaning solutions
Brittle nail
PACHYONYCHIA CONGENITA
 AD,very rare
 Hypertrophy of nails occurs a/w nail bed
hyperkeratosis
 PC 1: Normal by birth,Progressively
discoloured,thicken more on hands,Palmo-
plantar hyperkeratosis & warty lesions at
knee,elbows,buttocks,Defect Keratins 6a
& 16
 PC 2: Less severe nail thickening &
Keratosis, a/w hamartomas,Kinky scalp
hair,epidermal cysts,Defect keratins 6b &
17
PACHYONYCHIA CONGENITA
ALTERATIONS IN NAIL SIZE
ANONYCHIA
ABSENCE OF ALL OR PART OF ONE OR SEVERAL NAILS
 Congenital:
Mutation in R- Spondin 4
gene
 Transient :
Due to nail shedding
 Acquired:
Due to scarring of nail
matrix
Trauma,Burns,Surgery,
Lichenplanus.
Epidermolysis bullosa-
irreversible nail loss
ANONYCHIA
 It is a/w DOOR syndrome,AEC
syndrome,EEC syndrome,TOOD syndrome
 Anonychia atrophica : it is an acquired nail
dystrophy,Permanent,secondary to nail
matrix damage
ANONYCHIA
Congenital absence of nails in child
MICRONYCHIA
 Nails Smaller
 Uni or Bilateral
 Identifies in Iso- Kikuchi
syndrome,Zimmerman-Laband
syndrome,Turners syndrome
MACRONYCHIA
 Naila are larger
 Uni Or Bilateral
 It is a/w Macrodactyly as in
Vonrecklinnghausens disease,Maffucci
syndrome,Klippel-Trenaunay-Weber
syndrome
POLYNYCHIA
 Existence of two or more separate nails on
one digit
 Rare Congenital anomaly
 Lawrence-Moon-Biedl syndrome
POLYNYCHIA
RACKET NAILS
 AD
 Girls > Boys
 Thumbs >> Other fingers
 Epiphyses of terminal phalanx of thumb
closes prematurely by age of 7-
10yrs,normally at 13-14 yrs
 Distal phalanx of affected thumb is shorter
& wider than normal
 Affected nails are opaque,short with loss
of normal curvature
 Acquired: cong syphilis,acro osteolysis
RACKET NAILS
NAIL PATELLA SYNDROME
 AD
 Nails partially or totally absent
 Linkage b/w locus controlling disorder &
ABO blood group
 LMX1B gene plays imp role,located on
long arm of ch 9
 Tetrad constitutes Nail
dystrophy,Hypoplastic or absent
patellae,Elbow dysplasia,Iliac horns
 Thumb >> other finger
 Affected nails 1/3 or 1/2 of normal size
NAIL PATELLA SYNDROME
 Lunula are triangular or V shaped
 Bilateral Post Iliac horns on x-ray
Pathognomonic
 Prenatal diagnosis by USG Possible
 Other features Lester iris,Open angle
glaucome,Palmoplantar hyperhidrosis,
Scapular hypoplasia
NAIL PATELLA SYNDROME
Traingular Lunula
ISO KIKUCHI SYNDROME
 Nails of index finger small or absent
 Unilateral or bilateral
 Miconychia is MC presentation
 Terminal bifurcation of distal phalanx is
characteristic feature
DOLICHONYCHIA
 Nails appear narrow & long
 Normally ratio b/w length & breadth of nail is
1 + 0.1
 In these condition about 1.9
 Identified in Ehlers danlos syndrome,Marfans
syndrome
CIRCUMFERENTIAL NAILS
 Nails are Tubular
 Congenital seen in siblings
 Nails may cover all sides of one or more
fingers
CONGENITAL MALALIGNMENT OF BIGTOE
 Lateral deviation of long axis of nail growth
relative to distal phalanx one big toe or
both
 Medial deviation is rare
 Nails discoloured & thickened,often
traingular in shape
 MC identified in Monozygotic & Dizygotic
twins
 Nail grows temporarily fast than bone of
hallux,Realignment occurs when bone
growth catches up with nail post natally
PERIODIC SHEDDING
 Nails of great toe MC affected
 AD
 One or more nails shed repeatedly
 Regrowth of nail incomplete,defective
 Trauma from ill fitting shoes is MC cause of
repeated shedding of nails in sports persons
ALTERATIONS IN NAIL SHAPE
CLUBBING
 Increased Transverse & Longitudinal nail
curvature with hypertrophy of soft tissue
components of digital pulp
 Hyperplasia of fibrovascular tissue at base of
nail gives Rocked nail appearance
 Lovibonds angle, Curths angle, Schamroth’s
window
 Also K/A Hippocratic nails ,Watch glass nails
CLUBBING
Patient with cystic fibrosis
CLUBBING
 Increased blood flow through vasodilated plexus of
nail unit vasculature > Vessel hyperplasia
 Altered Vagal tone
 Microvascular infarcts
 PDGF may responsible for vascular changes
 Painful clubbing indicative of periostitis associated
with HPOA,characteristic of thoracic malignancy
 Pachydermoperiostosis : idiopathic,Puberty,a/w
spade like thickening of foot & hands
CLUBBING
SHELL NAILS RACKET NAILS
 Similar to clubbed nails
 Girls with bronchiectasis
around 5 yrs age
 Avulsion of nail plate
reveals atrophy of nail bed
instead of hypertrophy
noted in true clubbing
 Broad & Shortened nails
usually seen thumb & great
toes
 Similar to clubbed nails D/T
stubby appearance
 Arrest in distal phalangeal
formation
CLUBBING
 Lovibond angle : angle
at junction of nail plate
& proximal nail fold
 Normally less than 160
degrees
 Clubbing angle is more
than 180 degrees
CLUBBING
 Curth’s angle : Angle at
Distal interphalangeal
joint
 Normally 180 degrees
 Clubbing diminished
less than 160 degrees
RACKET NAIL WITH CLUBBING RACKET NAILS
DISEASES OF NAIL BED
PSORIASIS
 Multiple nail pits on
dorsal nail plate
 Oil staining of nail bed
 Distal Onycholysis
PSORIASIS
 Rough surface
(Trachonychia )
 Distal onycholysis
 Oil Staining
PSORIASIS
 Punctate Leukonychia
 Pathognomic
 Traumatic subungual
haemorrhage
PSORIASIS
 Oil staining
 Longitudinal ridging
 Distal onycholysis
 Adherence of cuticle to
distal nail plate
PSORIASIS
Spongitic Pustule seen in Epidermis Absence of Granular layer,Acanthosis
of Epidermis,Vascular Changes
LICHEN PLANUS
 Nail involvement seen in 10 % of patients
with LP
 Nail thinning,ridging & fissuring
 Cicatricial out come ( Dorsal Pterygium )
 Yellowish discolouration
 Onycholysis
LICHEN PLANUS
 Middle Finger :
Proximal nail fold and
matrix caused
trachonychia,Longitudin
al ridging,pterygium
 Index Finger :
Destruction of Nail
Plate & Matrix with
anonychia
LICHEN PLANUS
 Involvement of nail
matrix with pterygium
 Scarring
 Pt had Hepatitis C virus
with erosive lichen
planus
LICHEN PLANUS
 Involvement of nail
matrix
 Thinning of thumbnail
plates
LICHEN PLANUS :
Lichenoid infiltrate of nail bed and distal nail
matrix * ,Nail plate
LICHEN PLANUS
HYPERKERATOSIS & SUPERFICIAL
LYMPHOCYTIC INFILTRATE
BAND LIKE SUPERFICIAL LYMPHOCYTIC INFILTRATE
ALONG WITH VACUOLAR DEGENRATION
DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)
 Nail involvement in 96% cases
 Red or white longitudinal streaks ending in a V
shaped notch
 Streaks indicative of nail thinning
 Subungual hyper keratotic papules in
hyponychium
 Histologically similar to acantholysis of skin in
addition of multinucleated giant cells,epithelial
hyperplasia seen
 A case of SCC developing in chronic case of
darier disease also noted
DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)
 Longitudunal streaks (
red & white )
 Distal subungual
hyperkeratotic papules
 Wedge shaped fissuring
of nail plate
DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)
 White and Red
Longitudinal streaks
 Distal notching
RED LUNULA
 Erythema of all or part of the lunula may
affect all digits, but most prominently the
thumb
 Dotted red lunulae have been reported in
psoriasis and alopecia areata
 red lunula seen in a single digit-Local
disturbance of vascular flow- Benign
tumour
 Glomus tumour & Subungual myxoid cysts
MC tumours.colour vary from blue & red
YELLOW NAIL SYNDROME
 The nails are yellow due to
thickening,rarely green tinge possibly due
to secondary infection
 There is increased transverse &
longitudinal curvature,loss of cuticle &
Lunula obscured
 AD
 A/w lymphoedema at one or more sites
and respiratory or nasal sinus disease
YELLOW NAIL SYNDROME
 Histologically dense fibrous tissue
replacing Subungual stroma with
numerous ectatic epithelium lined
vessels,FB reaction may be seen
 Obstruction of lymphatics by dense stroma
leads to the abnormal lymphatic function
found in the affected digits
 Recurrent pleural effusions,Ch bronchitis,
bronchiectasis,increased incidence of
malignant neoplasms,nephrotic syndrome
YELLOW NAIL SYNDROME
 Nails grow at slower rate 0.1-0.25
mm/week ( normal rate 0.5mm/week )
YELLOW NAIL SYNDROME
 Diffuse Yellow to Green
of nails
 Nail thickening
 Excessive curvature of
from side to side
YELLOW NAIL SYNDROME
 Treatment :
- Oral & Topical Vit E
- Oral & Topical Zn
- Pulse Itraconazole 400mg daily /week/month
- Treatment of Chronic infection
- Complete reversion of nail changes may
occur spontaneously
HUTCHINSON’S SIGN
 Brown black periungual pigmentation
 Possible sign of nail melanoma
 First described by Hutchinson ,Pigmentation
of proximal nail fold in a/w longitudinal
melanonychia
 Also identified in melanocytic naevi
HUTCHINSON’S SIGN
GREEN NAIL SYNDROME
 Greenish black discolouration d/t Pyocyanin
by P. aeruginosa
 Exposure to water,detergents & soaps
 Barbers,Bakers & Dish washers
 DD: Melanoma,Aspergillus,Melanocytic
naevus
 Rx:Aminoglycosides,Acetic acid for 1 to 4
months
MEE'S LINES
 Transverse white lines that run across the
nail, following the shape of the nail moon
 Uncommon
 after acute/severe illness, Arsenic poisoning
MEE'S LINES
BROWN – GRAY NAILS
CYANOSIS
 A bluish discoloration visible at the nail
bases
 patient with severe hypoxemia or
hypoperfusion.
CYANOSIS
HALF-&-HALF NAILS
 K/a Lindsay's nails
 Look for an arc of brownish discoloration
 May occur in a small percentage of people
who have ch renal failure
 Other causes systemic diseases & nutritional
deficiencies
HALF-&-HALF NAILS
SPLINTER HAEMORRHAGES
 Looks like a splinter underneath the nail
 virtually 100% diagnostic of Sub-acute
Bacterial Endocarditis (SBE)
 A bacterial infection affecting the valves of
the heart. Occasionally caused by
Trichinosis, a parasitic infection caused by
eating raw or undercooked Pork.
SPLINTER HAEMORRHAGES
MELANONYCHIA
 vertical pigmented bands or nail 'moles‘
 a sudden change in the nail plate could
indicate a malignant melanoma or lesion.
 Commonly occur in dark-skinned people, and
are normal
 Seek physicians care ,If you suddenly see
this change in the nail plate.
MELANONYCHIA
LEUKONYCHIA
WHITE DISCOLOURATION OF NAILS
 True Leukonychia:
Inherited disorder,all nail
affected,milky porcelian white
nails
 Subtotal Leukonychia :
Proximal 2/3rd white rest pink d/t
delay in keratin maturation
 Transverse Leukonychia:
k/a Mees lines reflect systemic
disorder,chemotheraphy,poisini
ng
 Punctate Leukonychia:
White spots of 1-3 mm
size,Manicure,alopecia areata
 Apparent Leukonychia:
Changes in nail bed responsible
for white appearance
 Terry’s Nails: white
proximally,normal distally,seen
in old age,chronic renal
failure,afterchemotheraphy,cirr
hosis,cardiac failure,histology
shows Inc vessel wall
thickness & Melanin deposition
 Muehrcke’s paired white bands
: bands parallel to lunula in nail
bed with pink in b/w white
lines,seen in
hypoalbuminaemia
LEUKONYCHIA
White nails in distal free edges
TERRY'S NAILS
 The nail looks opaque
and white, but the nail
tip has a dark pink to
brown band.
 May accompany
cirrhosis, congestive
heart failure, adult-
onset diabetes, cancer
or ageing.
ECZEMA OF THE NAIL
 It affect the eponychium, nail plate and bed
 It causing pitting and onycholysis.
This is very rare
Eczema
HANG NAILS
 Caused by minor injury or constant irritation through biting.
The cuticle splits and appears as a small spike.
 Hot oil manicures and regular use of a cuticle oil will help.
The spike can be clipped so it does not catch on things.
EGGSHELL NAIL
 Nail plate is thin and
abnormally flexible
 chronic illness of
systematic or nervous
origin
 It curves at the free
edge and the nail plate
can separate from the
nail bed
ONYCHOLYSIS
DISTAL OR LATERAL SEPARATION OF NAIL FROM NAIL BED
 Psoriatic onycholysis considered as a reference
point for other forms
 PO-typically distal,variable lateral involvement,area
of separation appear white or yellow due to air
beneath the nail,sequestered debris & glycoprotien
exudate
 Isolated islands of onycholysis present as Oil spots
, salmon patches
ONYCHOLYSIS
 Idiopathic
-Painless separation of nail from
its bed
-Overzealous manicure,
wetting,cosmetic solvents
-Condition starts at tip of
nail,spreads to distal one third
of nail bed
-Colonization of candida albicans
& pseudomonas pyocyanea
-Affected nails grow very
quickly,more in women,
 Secondary
- Psoriasis,trauma,fungal
infections,dermatitis,hypo
thyroidism,yellow nail
syndrome,shell nail
syndrome
- Photoonycholysis :
treatment
withpsoralens,doxycyclin
e,demethylchlortetracycli
ne,retinoids,anti cancer
drugs
ONYCHOLYSIS
 Distal onycholysis
 Loss of cuticle
 Psoriasis may be cause
ONYCHOLYSIS
 Most commonly associated with external trauma to the nail
 Nail plate separates from the nail bed
ONYCHOLYSIS
The subungual space
may be filled with
hyperkeratotic debris
Distal nail bed separated from the nail plate in 2 nails.
ONYCHOLYSIS
 Treatment :
- Patient advised cut away loosened nail & apply
local steroid with antibiotics ( prevent keratinisation
of nail bed,that slows reattachment of nail)
- Gentamicin eye drops for pseudomonas infection
- 2% thymol in chloroform for preventing infection
- Milton regimen : soaking finger tips several nights
week in venegar or sodium hypochlorite solution for
5 mins for prevention of recurrence
ONYCHOMYCOSIS
 A fungal or yeast infection which results in
Onychomycosis, can invade through a tear in the
proximal and lateral nail folds as well as the
eponychium.
 This type of infection is characterized by
onycholysis with evident debris under the nail plate.
 It normally appears white or yellowish in color, and
may also change the texture and shape of the nail.
 The fungus digests the keratin protein of which the
nail plate is comprised. As the infection progresses,
organic debris accumulates under the nail plate
often discoloring it.If left untreated, the nail plate
may separate from the nail bed and crumble off.
ONYCHOMYCOSIS
(TINEA UNGUIUM)
 White spots that can be scraped off the surface, or long yellowish
streaks within the nail substance.
 It attacks the free edge & moves towards the matrix
ONYCHOMYCOSIS
TINEA UNGUIUM – NAIL INFECTION
ONYCHOMYCOSIS
DSO
Distal subungual
hyperkeratosis and
onycholysis
involving most of
the nail bed of the
great toenails; these
findings are
usually associated
with tinea pedis.
Onychomycosis
ONYCHOMYCOSIS
NAIL CLIPPINGS SHOW SEPTATE
HYPHAL ELEMENTS PROVEN TO BE
TRICHOPHYTON SP WITH IN NAIL
PLATE KERATIN
 90 % Toe nail infections with
Trichophyton,Microsporum,Ep
idermophyton sp
 PAS staining most sensitive
test
 Stain reveals fungal
organisms located in lower
stratum corneum
 Distal subungual
Onychomycosis is MC
form,caused by T.rubrum
 It invades hyponychium &
LNF finally
yellow,onycholysis,sub ungual
hyperkeratosis
 T.mentagrophytes identified in
superficial white OM,located
ONYCHOPHAGY
 Bitten nails, often no free edge is visible
 Nails look ragged and distorted
 skin and nail bed can be exposed and raw
ONYCOPHOSIS
 Refers to the growth of the horny epithelium
in the nail bed
 In other words a callus like growth on the
nail plate
ONYCHOGRYPHOSIS
 Elderly,Commonly toenails,usually Hallux
 Favored by trauma
 Impairement of peripheral circulation and
innervation
 Nail acquires typical Ram’s Horn shape d/t
asymmetric growth
 Thick,hard,yellow brown nails
ONYCHOPTOSIS
 Periodic shedding of one or more nails,
either in whole or parts
 This condition may follow certain diseases
such as syphilis
PARONYCHIA
 Paronychia is associated with separation of
the seal between the proximal nail fold and
the nail plate that provides entry for bacteria
and leads to a localized infection of the
paronychial tissues of the hands.
 Symptoms may include inflammation,
swelling & scaling
PARONYCHIA
 An infectious and
inflammatory condition
of nail folds. Infection is
bacterial
 Ch paronychia may
weaken defences and
increase the risk of
developing a fungal
infection of the nail
PARONYCHIA
The nail fold is
erythematous,
edematous, with
early abscess
formation, and is
very painful.
Paronychia
PTERYGIUM
 Pterygium is the inward advance of skin over
the nail plate,
 Usually as a result of trauma to the matrix due
to a surgical procedure or by a deep cut to the
nail plate
 Pterygium results in the loss of the nail plate due
to the development of scar tissue
 Cortisone is used to prevent the advancement of
scar tissue. Never attempt to remove pterygium
-instead, consult a physician for advice and
treatment
 NOTE: The 'true cuticle' is often referred to as
Pterygium
PTERYGIUM
 Pterygium Inversum Unguis is an acquired
forward growth of the hyponychium
characterized by live tissue firmly attached
to the underside of the nail plate, which
contains a blood supply and nerves.
 Possible causes are systemic, hereditary,
or from an allergic reaction to acrylics or
solvents.
 Never use force to 'push back' the
advancing hyponychium -- it is an
extremely painful approach, and will result
in a blood flow.
PTERIGIUM
 An abnormal winged like
growth of skin (living
tissue) on the nail plate
 The skin is slowly
stretched and dragged
along the bed
 caused by severe trauma
such as warts, burns &
blood circulation
disorders.
PTERYGIUM
DORSAL PTERYGIUM
VENTRAL PTERYGIUM
SCABIES OF NAIL
 Commonly identified in crusted scabies
 Heaped up masses of keratin accummulate
underneath the nail
 Subungual material contains abundant
mites,source of infection
 Nails become dystrophic
SCABIES OF NAIL
SCABIES OF NAIL
 Sarcoptes scabiei
present in distal
subungual
hyperkeratotic debris
found in hyponychium
 Cause of persistent
epidemics of scabies
 Norwegian scabies
severe involvement of
nail folds
Scrapings of distal hyponychium-
showing organism – Sarcoptes Scabiei
CANDIDA
 Candida parapsilosis account for 20%
infections
 Candida common cause of Chronic
paronychia,involve nail bed & nail plate in
HIV
 Candida albicans major cause of hypertropic
nail bed infection in paediatric patients with
HIV
CANDIDAL PARONYCHIA
MUCOCUTANEOUS CANDIDIASIS
CANDIDA
NAIL CLIPPINGS SHOW BUDDING
YEASTS
PSEUDOMONAS
 Pseudomonas bacterial infection can occur
between the natural nail plate and the nail bed
 Many people have been led to believe that the
classic 'green' discoloration of this type of
infection is some type of mold
 In actuality, mold is not a human
pathogen. The discoloration is simply a by-
product of the infection and is caused primarily
by iron compounds

PSEUDOMONAS
 Pseudomonas thrive in moist places; it
feeds off the dead tissue and bacteria in
the nail plate, while the moisture levels
allow it to grow
 The after effects of this infection will
cause the nail plate to darken and soften
underneath an artificial coating
PSEUDOMONAS
 The darker the discoloration, the deeper into
the nail plate layers the bacteria has
traveled. If the bacteria has entered between
the nail plate and the nail bed, it will cause
the same discolorations and may also cause
the nail plate to lift from the nail bed.
PSEUDOMONAS
 pseudomonas
colonisation
ALOPECIA AREATA
 First sign in 18% cases,More in children
 Pitting of nails,When pits uniformily
distributed on multiple nails,they often
arranged in lines horizontially or vertically in
a geometrical design k/a Glen-Plaid or
Scotch-Plaid Pattern
ALOPECIA AREATA
SCOTCH-PLAID PATTERN
ASSESSING NAIL DISORDERS
 Social History
 Footwear
 Medical History
 Physical exam
 Nail Assessment
 Special Investigations
SOCIAL HISTORY
 Smoking
 Occupation
 Recreational Activities
 Places of residences (Qsld)
FOOTWEAR
 Occupational
 Recreational
 Historical
 May need to inspect footwear
MEDICAL HISTORY
 Need to conduct a review of systems (ROS)
 Dermatological Conditions important
 eg psoriasis, atopy,
 Multi-System Disorders
 eg RA, SLE, DE, CREST
 Cardiac/Pulmonary Problems
 Medications review
 Surgical Review
 Genetics review
PHYSICAL EXAMINATION
 Vascular
 macro/micro circulation
 Neurological
 Deficits?
 Dermatological
 Below Knee
 Gait Assessment
SUBJECTIVE NAIL ASSESSMENT
 Events of Note
 How long has problem been present?
 Is it getting better or worse?
 Is it of concern to the client?
 Is pain present?
 If so need to evaluate pain
 What previous treatments have been attempted?
 Professional
 OTC
 Folk
 Need to follow up if any of these answers is positive
OBJECTIVE ASSESSMENT OF NAILS
 Number of nails affected?
 Hands involved?
 Colour changes
 Extent of colour changes
 Extent of general changes
 Presence of toe deformity
 Presence of local exostosis
 May need to examine other areas
 Scalp, elbows, knees
SPECIAL INVESTIGATIONS
 Nail Specific
 Biopsy
 Microscopy (KOH test)
 Culture
 X-Ray
 Blood Tests
 Further Vascular/Neurological Testing
 Cardiac Evaluation
 Genetic Testing
COMMON AETIOLOGIES
 Trauma
 Infection
 Fungal
 Bacterial
 Systemic Disorders
 Direct
 Indirect
 Neoplasms
THANK YOU
PLEASE SHOOT QUESTIONS AT
dryugmd@gmail.com

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Applied aspects of nail

  • 1. ALTERATIONS IN THE NAIL PLATE DR. YUGANDAR
  • 2. KOILONYCHIA  Reverse curvature in longitudinal & Transverse axes giving a concave dorsal aspects of nail  Signs most prominent in great toe & thumb  Iron def anemia in adults  Common feature in infancy great toe nail,persistence indicative of deficiency of cysteine rich keratin in Trichothiodystrophy
  • 3. KOILONYCHIA -Spoon shaped deformity -Normal Convexity replaced by Central Concavity -Surrounded by Distal & Lateral Margins -Lichenplanus,hypothyroidism, hemochromatosis,20- nail dystrophy
  • 5. BEAUS LINES  Single horizontal ridge by horizontal lines of darkened cells and linear depressions  It is the result of any interruption in the protein formation of the nail plate  trauma, illness, malnutrition or any major metabolic condition, chemotherapy
  • 6. BEAU’S LINES  Multiple transverse ridging  Chemotheraphy with Breast Cancer
  • 9. TRACHYONYCHIA (20-NAIL DYSTROPHY,SANDPAPERED NAILS)  Rough surface affecting all nail plates,idiopathic forms k/s 20 nail dystrophy  k/a Sand Blasted Nails in French means grey,roughened surface  Alopecia areata, Psoriasis,Lichen planus  Histology shows spongiosis & lymphocytic infiltrate
  • 10. ONYCHOMADESIS(NAIL SHEDDING)  Detachment of the nail plate from proximal nail fold,d/t severe insult that produces arrest of nail matrix activity  Proximal detachment of nail  Most often traumatic
  • 11. ONYCHAUXIS GREAT TOE NAILS GROSSLY THICKENED WITH TRANSVERSE RIDGING ( ONYCHAUXIS )  Nail thickening d/t subungual scales  Subungual hyperkeratosis  psoriasis,onychomycosis,e czema
  • 12. ONYCHIA • Inflammation of the nail matrix • It is accompanied by pus formation • There is Inflammation within the nail plate
  • 13. ONYCHOCRYPTOSIS (INGROWN TOE NAIL)  Lateral ingrowing usually affects hallux, great toe  Teenagers,Young adults,congenital malalignment of big toes nails often present  Ppt by improper nail cutting and hyperhidrosis  Growth of granulation tissue undergoes epithelialization  DD: Multiple Periungual Pyogenic granulomas d/t retinoids,ART drugs
  • 14. ONYCHOCRYPTOSIS :TREATMENT  Prevention through patient education  Removal of embeded spicule  Uplifting of lateral nail plate  Chemical – 80% Phenol,Laser or Surgical removal of Lateral Matrix in severe cases  Granulation tissue prevented by topical antibiotics & steroids,
  • 15. ONYCHOCRYPTOSIS (INGROWN NAILS)  Also known as ingrown nails  May affect either the fingers or toes The nail grows into the sides of the flesh & may cause infection
  • 17. HABIT TIC DEFORMITY  Dystrophic nails  Transverse ridging  Absent of cuticle  Excoriation of Proximal nail fold
  • 18. ONYCHORRHEXIS  Brittle nails,split vertically, peel or have vertical ridges.  The result of heredity, the use of strong solvents in the workplace or the home, including household cleaning solutions.  Lichen Planus,tumours which compromise vascular supply
  • 19. ONYCHORRHEXIS  Thinning of Nail plate  Longitudinal ridging & fissuring  Mild Longitudinal ridging is characteristic of Ageing
  • 20. ONYCHOGRYPOSIS  Claw-type nails that are characterized by a thickened nail plate  Often the result of trauma  This type of nail plate will curve inward, pinching the nail bed and sometimes require surgical intervention to relieve the pain.
  • 21. ONYCHATROPHIA  It is an atrophy or wasting away of the nail plate  which causes it to lose its luster, become smaller & sometimes shed entirely  Injury or disease may account for this irregularity
  • 22. PINCER NAILS  Painful abnormality of nails  Toe >> finger nails  a/w subungual exostosis  Distal nail plate over curved & compresses subungual tissue
  • 23. BRITTLE NAILS  a vertical splitting or separation of the nail plate layers at the distal (free) edge of the nail plate  characteristic of the natural aging process.  overexposure to water and chemical solvents such as household cleaning solutions
  • 25. PACHYONYCHIA CONGENITA  AD,very rare  Hypertrophy of nails occurs a/w nail bed hyperkeratosis  PC 1: Normal by birth,Progressively discoloured,thicken more on hands,Palmo- plantar hyperkeratosis & warty lesions at knee,elbows,buttocks,Defect Keratins 6a & 16  PC 2: Less severe nail thickening & Keratosis, a/w hamartomas,Kinky scalp hair,epidermal cysts,Defect keratins 6b & 17
  • 28. ANONYCHIA ABSENCE OF ALL OR PART OF ONE OR SEVERAL NAILS  Congenital: Mutation in R- Spondin 4 gene  Transient : Due to nail shedding  Acquired: Due to scarring of nail matrix Trauma,Burns,Surgery, Lichenplanus. Epidermolysis bullosa- irreversible nail loss
  • 29. ANONYCHIA  It is a/w DOOR syndrome,AEC syndrome,EEC syndrome,TOOD syndrome  Anonychia atrophica : it is an acquired nail dystrophy,Permanent,secondary to nail matrix damage
  • 31. MICRONYCHIA  Nails Smaller  Uni or Bilateral  Identifies in Iso- Kikuchi syndrome,Zimmerman-Laband syndrome,Turners syndrome
  • 32. MACRONYCHIA  Naila are larger  Uni Or Bilateral  It is a/w Macrodactyly as in Vonrecklinnghausens disease,Maffucci syndrome,Klippel-Trenaunay-Weber syndrome
  • 33. POLYNYCHIA  Existence of two or more separate nails on one digit  Rare Congenital anomaly  Lawrence-Moon-Biedl syndrome
  • 35. RACKET NAILS  AD  Girls > Boys  Thumbs >> Other fingers  Epiphyses of terminal phalanx of thumb closes prematurely by age of 7- 10yrs,normally at 13-14 yrs  Distal phalanx of affected thumb is shorter & wider than normal  Affected nails are opaque,short with loss of normal curvature  Acquired: cong syphilis,acro osteolysis
  • 37. NAIL PATELLA SYNDROME  AD  Nails partially or totally absent  Linkage b/w locus controlling disorder & ABO blood group  LMX1B gene plays imp role,located on long arm of ch 9  Tetrad constitutes Nail dystrophy,Hypoplastic or absent patellae,Elbow dysplasia,Iliac horns  Thumb >> other finger  Affected nails 1/3 or 1/2 of normal size
  • 38. NAIL PATELLA SYNDROME  Lunula are triangular or V shaped  Bilateral Post Iliac horns on x-ray Pathognomonic  Prenatal diagnosis by USG Possible  Other features Lester iris,Open angle glaucome,Palmoplantar hyperhidrosis, Scapular hypoplasia
  • 40. ISO KIKUCHI SYNDROME  Nails of index finger small or absent  Unilateral or bilateral  Miconychia is MC presentation  Terminal bifurcation of distal phalanx is characteristic feature
  • 41. DOLICHONYCHIA  Nails appear narrow & long  Normally ratio b/w length & breadth of nail is 1 + 0.1  In these condition about 1.9  Identified in Ehlers danlos syndrome,Marfans syndrome
  • 42. CIRCUMFERENTIAL NAILS  Nails are Tubular  Congenital seen in siblings  Nails may cover all sides of one or more fingers
  • 43. CONGENITAL MALALIGNMENT OF BIGTOE  Lateral deviation of long axis of nail growth relative to distal phalanx one big toe or both  Medial deviation is rare  Nails discoloured & thickened,often traingular in shape  MC identified in Monozygotic & Dizygotic twins  Nail grows temporarily fast than bone of hallux,Realignment occurs when bone growth catches up with nail post natally
  • 44. PERIODIC SHEDDING  Nails of great toe MC affected  AD  One or more nails shed repeatedly  Regrowth of nail incomplete,defective  Trauma from ill fitting shoes is MC cause of repeated shedding of nails in sports persons
  • 46. CLUBBING  Increased Transverse & Longitudinal nail curvature with hypertrophy of soft tissue components of digital pulp  Hyperplasia of fibrovascular tissue at base of nail gives Rocked nail appearance  Lovibonds angle, Curths angle, Schamroth’s window  Also K/A Hippocratic nails ,Watch glass nails
  • 48.
  • 49. CLUBBING  Increased blood flow through vasodilated plexus of nail unit vasculature > Vessel hyperplasia  Altered Vagal tone  Microvascular infarcts  PDGF may responsible for vascular changes  Painful clubbing indicative of periostitis associated with HPOA,characteristic of thoracic malignancy  Pachydermoperiostosis : idiopathic,Puberty,a/w spade like thickening of foot & hands
  • 50. CLUBBING SHELL NAILS RACKET NAILS  Similar to clubbed nails  Girls with bronchiectasis around 5 yrs age  Avulsion of nail plate reveals atrophy of nail bed instead of hypertrophy noted in true clubbing  Broad & Shortened nails usually seen thumb & great toes  Similar to clubbed nails D/T stubby appearance  Arrest in distal phalangeal formation
  • 51. CLUBBING  Lovibond angle : angle at junction of nail plate & proximal nail fold  Normally less than 160 degrees  Clubbing angle is more than 180 degrees
  • 52. CLUBBING  Curth’s angle : Angle at Distal interphalangeal joint  Normally 180 degrees  Clubbing diminished less than 160 degrees
  • 53.
  • 54. RACKET NAIL WITH CLUBBING RACKET NAILS
  • 56. PSORIASIS  Multiple nail pits on dorsal nail plate  Oil staining of nail bed  Distal Onycholysis
  • 57. PSORIASIS  Rough surface (Trachonychia )  Distal onycholysis  Oil Staining
  • 58. PSORIASIS  Punctate Leukonychia  Pathognomic  Traumatic subungual haemorrhage
  • 59. PSORIASIS  Oil staining  Longitudinal ridging  Distal onycholysis  Adherence of cuticle to distal nail plate
  • 60. PSORIASIS Spongitic Pustule seen in Epidermis Absence of Granular layer,Acanthosis of Epidermis,Vascular Changes
  • 61. LICHEN PLANUS  Nail involvement seen in 10 % of patients with LP  Nail thinning,ridging & fissuring  Cicatricial out come ( Dorsal Pterygium )  Yellowish discolouration  Onycholysis
  • 62. LICHEN PLANUS  Middle Finger : Proximal nail fold and matrix caused trachonychia,Longitudin al ridging,pterygium  Index Finger : Destruction of Nail Plate & Matrix with anonychia
  • 63. LICHEN PLANUS  Involvement of nail matrix with pterygium  Scarring  Pt had Hepatitis C virus with erosive lichen planus
  • 64. LICHEN PLANUS  Involvement of nail matrix  Thinning of thumbnail plates
  • 65. LICHEN PLANUS : Lichenoid infiltrate of nail bed and distal nail matrix * ,Nail plate
  • 66. LICHEN PLANUS HYPERKERATOSIS & SUPERFICIAL LYMPHOCYTIC INFILTRATE BAND LIKE SUPERFICIAL LYMPHOCYTIC INFILTRATE ALONG WITH VACUOLAR DEGENRATION
  • 67. DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)  Nail involvement in 96% cases  Red or white longitudinal streaks ending in a V shaped notch  Streaks indicative of nail thinning  Subungual hyper keratotic papules in hyponychium  Histologically similar to acantholysis of skin in addition of multinucleated giant cells,epithelial hyperplasia seen  A case of SCC developing in chronic case of darier disease also noted
  • 68. DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)  Longitudunal streaks ( red & white )  Distal subungual hyperkeratotic papules  Wedge shaped fissuring of nail plate
  • 69. DARIER-WHITE DISEASE (KERATOSIS FOLLICULARIS)  White and Red Longitudinal streaks  Distal notching
  • 70. RED LUNULA  Erythema of all or part of the lunula may affect all digits, but most prominently the thumb  Dotted red lunulae have been reported in psoriasis and alopecia areata  red lunula seen in a single digit-Local disturbance of vascular flow- Benign tumour  Glomus tumour & Subungual myxoid cysts MC tumours.colour vary from blue & red
  • 71. YELLOW NAIL SYNDROME  The nails are yellow due to thickening,rarely green tinge possibly due to secondary infection  There is increased transverse & longitudinal curvature,loss of cuticle & Lunula obscured  AD  A/w lymphoedema at one or more sites and respiratory or nasal sinus disease
  • 72. YELLOW NAIL SYNDROME  Histologically dense fibrous tissue replacing Subungual stroma with numerous ectatic epithelium lined vessels,FB reaction may be seen  Obstruction of lymphatics by dense stroma leads to the abnormal lymphatic function found in the affected digits  Recurrent pleural effusions,Ch bronchitis, bronchiectasis,increased incidence of malignant neoplasms,nephrotic syndrome
  • 73. YELLOW NAIL SYNDROME  Nails grow at slower rate 0.1-0.25 mm/week ( normal rate 0.5mm/week )
  • 74. YELLOW NAIL SYNDROME  Diffuse Yellow to Green of nails  Nail thickening  Excessive curvature of from side to side
  • 75. YELLOW NAIL SYNDROME  Treatment : - Oral & Topical Vit E - Oral & Topical Zn - Pulse Itraconazole 400mg daily /week/month - Treatment of Chronic infection - Complete reversion of nail changes may occur spontaneously
  • 76. HUTCHINSON’S SIGN  Brown black periungual pigmentation  Possible sign of nail melanoma  First described by Hutchinson ,Pigmentation of proximal nail fold in a/w longitudinal melanonychia  Also identified in melanocytic naevi
  • 78. GREEN NAIL SYNDROME  Greenish black discolouration d/t Pyocyanin by P. aeruginosa  Exposure to water,detergents & soaps  Barbers,Bakers & Dish washers  DD: Melanoma,Aspergillus,Melanocytic naevus  Rx:Aminoglycosides,Acetic acid for 1 to 4 months
  • 79. MEE'S LINES  Transverse white lines that run across the nail, following the shape of the nail moon  Uncommon  after acute/severe illness, Arsenic poisoning
  • 81. BROWN – GRAY NAILS
  • 82. CYANOSIS  A bluish discoloration visible at the nail bases  patient with severe hypoxemia or hypoperfusion.
  • 84. HALF-&-HALF NAILS  K/a Lindsay's nails  Look for an arc of brownish discoloration  May occur in a small percentage of people who have ch renal failure  Other causes systemic diseases & nutritional deficiencies
  • 86. SPLINTER HAEMORRHAGES  Looks like a splinter underneath the nail  virtually 100% diagnostic of Sub-acute Bacterial Endocarditis (SBE)  A bacterial infection affecting the valves of the heart. Occasionally caused by Trichinosis, a parasitic infection caused by eating raw or undercooked Pork.
  • 88. MELANONYCHIA  vertical pigmented bands or nail 'moles‘  a sudden change in the nail plate could indicate a malignant melanoma or lesion.  Commonly occur in dark-skinned people, and are normal  Seek physicians care ,If you suddenly see this change in the nail plate.
  • 90. LEUKONYCHIA WHITE DISCOLOURATION OF NAILS  True Leukonychia: Inherited disorder,all nail affected,milky porcelian white nails  Subtotal Leukonychia : Proximal 2/3rd white rest pink d/t delay in keratin maturation  Transverse Leukonychia: k/a Mees lines reflect systemic disorder,chemotheraphy,poisini ng  Punctate Leukonychia: White spots of 1-3 mm size,Manicure,alopecia areata  Apparent Leukonychia: Changes in nail bed responsible for white appearance  Terry’s Nails: white proximally,normal distally,seen in old age,chronic renal failure,afterchemotheraphy,cirr hosis,cardiac failure,histology shows Inc vessel wall thickness & Melanin deposition  Muehrcke’s paired white bands : bands parallel to lunula in nail bed with pink in b/w white lines,seen in hypoalbuminaemia
  • 91. LEUKONYCHIA White nails in distal free edges
  • 92. TERRY'S NAILS  The nail looks opaque and white, but the nail tip has a dark pink to brown band.  May accompany cirrhosis, congestive heart failure, adult- onset diabetes, cancer or ageing.
  • 93.
  • 94. ECZEMA OF THE NAIL  It affect the eponychium, nail plate and bed  It causing pitting and onycholysis. This is very rare
  • 96. HANG NAILS  Caused by minor injury or constant irritation through biting. The cuticle splits and appears as a small spike.  Hot oil manicures and regular use of a cuticle oil will help. The spike can be clipped so it does not catch on things.
  • 97. EGGSHELL NAIL  Nail plate is thin and abnormally flexible  chronic illness of systematic or nervous origin  It curves at the free edge and the nail plate can separate from the nail bed
  • 98. ONYCHOLYSIS DISTAL OR LATERAL SEPARATION OF NAIL FROM NAIL BED  Psoriatic onycholysis considered as a reference point for other forms  PO-typically distal,variable lateral involvement,area of separation appear white or yellow due to air beneath the nail,sequestered debris & glycoprotien exudate  Isolated islands of onycholysis present as Oil spots , salmon patches
  • 99. ONYCHOLYSIS  Idiopathic -Painless separation of nail from its bed -Overzealous manicure, wetting,cosmetic solvents -Condition starts at tip of nail,spreads to distal one third of nail bed -Colonization of candida albicans & pseudomonas pyocyanea -Affected nails grow very quickly,more in women,  Secondary - Psoriasis,trauma,fungal infections,dermatitis,hypo thyroidism,yellow nail syndrome,shell nail syndrome - Photoonycholysis : treatment withpsoralens,doxycyclin e,demethylchlortetracycli ne,retinoids,anti cancer drugs
  • 100. ONYCHOLYSIS  Distal onycholysis  Loss of cuticle  Psoriasis may be cause
  • 101. ONYCHOLYSIS  Most commonly associated with external trauma to the nail  Nail plate separates from the nail bed
  • 102. ONYCHOLYSIS The subungual space may be filled with hyperkeratotic debris Distal nail bed separated from the nail plate in 2 nails.
  • 103. ONYCHOLYSIS  Treatment : - Patient advised cut away loosened nail & apply local steroid with antibiotics ( prevent keratinisation of nail bed,that slows reattachment of nail) - Gentamicin eye drops for pseudomonas infection - 2% thymol in chloroform for preventing infection - Milton regimen : soaking finger tips several nights week in venegar or sodium hypochlorite solution for 5 mins for prevention of recurrence
  • 104. ONYCHOMYCOSIS  A fungal or yeast infection which results in Onychomycosis, can invade through a tear in the proximal and lateral nail folds as well as the eponychium.  This type of infection is characterized by onycholysis with evident debris under the nail plate.  It normally appears white or yellowish in color, and may also change the texture and shape of the nail.  The fungus digests the keratin protein of which the nail plate is comprised. As the infection progresses, organic debris accumulates under the nail plate often discoloring it.If left untreated, the nail plate may separate from the nail bed and crumble off.
  • 105. ONYCHOMYCOSIS (TINEA UNGUIUM)  White spots that can be scraped off the surface, or long yellowish streaks within the nail substance.  It attacks the free edge & moves towards the matrix
  • 107. TINEA UNGUIUM – NAIL INFECTION
  • 108. ONYCHOMYCOSIS DSO Distal subungual hyperkeratosis and onycholysis involving most of the nail bed of the great toenails; these findings are usually associated with tinea pedis.
  • 110. ONYCHOMYCOSIS NAIL CLIPPINGS SHOW SEPTATE HYPHAL ELEMENTS PROVEN TO BE TRICHOPHYTON SP WITH IN NAIL PLATE KERATIN  90 % Toe nail infections with Trichophyton,Microsporum,Ep idermophyton sp  PAS staining most sensitive test  Stain reveals fungal organisms located in lower stratum corneum  Distal subungual Onychomycosis is MC form,caused by T.rubrum  It invades hyponychium & LNF finally yellow,onycholysis,sub ungual hyperkeratosis  T.mentagrophytes identified in superficial white OM,located
  • 111. ONYCHOPHAGY  Bitten nails, often no free edge is visible  Nails look ragged and distorted  skin and nail bed can be exposed and raw
  • 112. ONYCOPHOSIS  Refers to the growth of the horny epithelium in the nail bed  In other words a callus like growth on the nail plate
  • 113. ONYCHOGRYPHOSIS  Elderly,Commonly toenails,usually Hallux  Favored by trauma  Impairement of peripheral circulation and innervation  Nail acquires typical Ram’s Horn shape d/t asymmetric growth  Thick,hard,yellow brown nails
  • 114. ONYCHOPTOSIS  Periodic shedding of one or more nails, either in whole or parts  This condition may follow certain diseases such as syphilis
  • 115. PARONYCHIA  Paronychia is associated with separation of the seal between the proximal nail fold and the nail plate that provides entry for bacteria and leads to a localized infection of the paronychial tissues of the hands.  Symptoms may include inflammation, swelling & scaling
  • 116. PARONYCHIA  An infectious and inflammatory condition of nail folds. Infection is bacterial  Ch paronychia may weaken defences and increase the risk of developing a fungal infection of the nail
  • 117. PARONYCHIA The nail fold is erythematous, edematous, with early abscess formation, and is very painful.
  • 119. PTERYGIUM  Pterygium is the inward advance of skin over the nail plate,  Usually as a result of trauma to the matrix due to a surgical procedure or by a deep cut to the nail plate  Pterygium results in the loss of the nail plate due to the development of scar tissue  Cortisone is used to prevent the advancement of scar tissue. Never attempt to remove pterygium -instead, consult a physician for advice and treatment  NOTE: The 'true cuticle' is often referred to as Pterygium
  • 120. PTERYGIUM  Pterygium Inversum Unguis is an acquired forward growth of the hyponychium characterized by live tissue firmly attached to the underside of the nail plate, which contains a blood supply and nerves.  Possible causes are systemic, hereditary, or from an allergic reaction to acrylics or solvents.  Never use force to 'push back' the advancing hyponychium -- it is an extremely painful approach, and will result in a blood flow.
  • 121. PTERIGIUM  An abnormal winged like growth of skin (living tissue) on the nail plate  The skin is slowly stretched and dragged along the bed  caused by severe trauma such as warts, burns & blood circulation disorders.
  • 123. SCABIES OF NAIL  Commonly identified in crusted scabies  Heaped up masses of keratin accummulate underneath the nail  Subungual material contains abundant mites,source of infection  Nails become dystrophic
  • 125. SCABIES OF NAIL  Sarcoptes scabiei present in distal subungual hyperkeratotic debris found in hyponychium  Cause of persistent epidemics of scabies  Norwegian scabies severe involvement of nail folds Scrapings of distal hyponychium- showing organism – Sarcoptes Scabiei
  • 126. CANDIDA  Candida parapsilosis account for 20% infections  Candida common cause of Chronic paronychia,involve nail bed & nail plate in HIV  Candida albicans major cause of hypertropic nail bed infection in paediatric patients with HIV
  • 128. CANDIDA NAIL CLIPPINGS SHOW BUDDING YEASTS
  • 129. PSEUDOMONAS  Pseudomonas bacterial infection can occur between the natural nail plate and the nail bed  Many people have been led to believe that the classic 'green' discoloration of this type of infection is some type of mold  In actuality, mold is not a human pathogen. The discoloration is simply a by- product of the infection and is caused primarily by iron compounds 
  • 130. PSEUDOMONAS  Pseudomonas thrive in moist places; it feeds off the dead tissue and bacteria in the nail plate, while the moisture levels allow it to grow  The after effects of this infection will cause the nail plate to darken and soften underneath an artificial coating
  • 131. PSEUDOMONAS  The darker the discoloration, the deeper into the nail plate layers the bacteria has traveled. If the bacteria has entered between the nail plate and the nail bed, it will cause the same discolorations and may also cause the nail plate to lift from the nail bed.
  • 133. ALOPECIA AREATA  First sign in 18% cases,More in children  Pitting of nails,When pits uniformily distributed on multiple nails,they often arranged in lines horizontially or vertically in a geometrical design k/a Glen-Plaid or Scotch-Plaid Pattern
  • 135. ASSESSING NAIL DISORDERS  Social History  Footwear  Medical History  Physical exam  Nail Assessment  Special Investigations
  • 136. SOCIAL HISTORY  Smoking  Occupation  Recreational Activities  Places of residences (Qsld)
  • 137. FOOTWEAR  Occupational  Recreational  Historical  May need to inspect footwear
  • 138. MEDICAL HISTORY  Need to conduct a review of systems (ROS)  Dermatological Conditions important  eg psoriasis, atopy,  Multi-System Disorders  eg RA, SLE, DE, CREST  Cardiac/Pulmonary Problems  Medications review  Surgical Review  Genetics review
  • 139. PHYSICAL EXAMINATION  Vascular  macro/micro circulation  Neurological  Deficits?  Dermatological  Below Knee  Gait Assessment
  • 140. SUBJECTIVE NAIL ASSESSMENT  Events of Note  How long has problem been present?  Is it getting better or worse?  Is it of concern to the client?  Is pain present?  If so need to evaluate pain  What previous treatments have been attempted?  Professional  OTC  Folk  Need to follow up if any of these answers is positive
  • 141. OBJECTIVE ASSESSMENT OF NAILS  Number of nails affected?  Hands involved?  Colour changes  Extent of colour changes  Extent of general changes  Presence of toe deformity  Presence of local exostosis  May need to examine other areas  Scalp, elbows, knees
  • 142. SPECIAL INVESTIGATIONS  Nail Specific  Biopsy  Microscopy (KOH test)  Culture  X-Ray  Blood Tests  Further Vascular/Neurological Testing  Cardiac Evaluation  Genetic Testing
  • 143. COMMON AETIOLOGIES  Trauma  Infection  Fungal  Bacterial  Systemic Disorders  Direct  Indirect  Neoplasms
  • 144. THANK YOU PLEASE SHOOT QUESTIONS AT dryugmd@gmail.com